Cargando…
Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population
Evolution is often conceived as changes in the properties of a population over generations. Does this notion exhaust the possible dynamics of evolution? Life is hierarchically organized, and evolution can operate at multiple levels with conflicting tendencies. Using a minimal model of such conflicti...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874703/ https://www.ncbi.nlm.nih.gov/pubmed/27147095 http://dx.doi.org/10.1098/rspb.2015.3109 |
_version_ | 1782433079097294848 |
---|---|
author | Takeuchi, Nobuto Kaneko, Kunihiko Hogeweg, Paulien |
author_facet | Takeuchi, Nobuto Kaneko, Kunihiko Hogeweg, Paulien |
author_sort | Takeuchi, Nobuto |
collection | PubMed |
description | Evolution is often conceived as changes in the properties of a population over generations. Does this notion exhaust the possible dynamics of evolution? Life is hierarchically organized, and evolution can operate at multiple levels with conflicting tendencies. Using a minimal model of such conflicting multilevel evolution, we demonstrate the possibility of a novel mode of evolution that challenges the above notion: individuals ceaselessly modify their genetically inherited phenotype and fitness along their lines of descent, without involving apparent changes in the properties of the population. The model assumes a population of primitive cells (protocells, for short), each containing a population of replicating catalytic molecules. Protocells are selected towards maximizing the catalytic activity of internal molecules, whereas molecules tend to evolve towards minimizing it in order to maximize their relative fitness within a protocell. These conflicting evolutionary tendencies at different levels and genetic drift drive the lineages of protocells to oscillate endlessly between high and low intracellular catalytic activity, i.e. high and low fitness, along their lines of descent. This oscillation, however, occurs independently in different lineages, so that the population as a whole appears stationary. Therefore, ongoing evolution can be hidden behind an apparently stationary population owing to conflicting multilevel evolution. |
format | Online Article Text |
id | pubmed-4874703 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-48747032016-05-25 Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population Takeuchi, Nobuto Kaneko, Kunihiko Hogeweg, Paulien Proc Biol Sci Research Articles Evolution is often conceived as changes in the properties of a population over generations. Does this notion exhaust the possible dynamics of evolution? Life is hierarchically organized, and evolution can operate at multiple levels with conflicting tendencies. Using a minimal model of such conflicting multilevel evolution, we demonstrate the possibility of a novel mode of evolution that challenges the above notion: individuals ceaselessly modify their genetically inherited phenotype and fitness along their lines of descent, without involving apparent changes in the properties of the population. The model assumes a population of primitive cells (protocells, for short), each containing a population of replicating catalytic molecules. Protocells are selected towards maximizing the catalytic activity of internal molecules, whereas molecules tend to evolve towards minimizing it in order to maximize their relative fitness within a protocell. These conflicting evolutionary tendencies at different levels and genetic drift drive the lineages of protocells to oscillate endlessly between high and low intracellular catalytic activity, i.e. high and low fitness, along their lines of descent. This oscillation, however, occurs independently in different lineages, so that the population as a whole appears stationary. Therefore, ongoing evolution can be hidden behind an apparently stationary population owing to conflicting multilevel evolution. The Royal Society 2016-05-11 /pmc/articles/PMC4874703/ /pubmed/27147095 http://dx.doi.org/10.1098/rspb.2015.3109 Text en © 2016 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Research Articles Takeuchi, Nobuto Kaneko, Kunihiko Hogeweg, Paulien Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
title | Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
title_full | Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
title_fullStr | Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
title_full_unstemmed | Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
title_short | Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
title_sort | evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874703/ https://www.ncbi.nlm.nih.gov/pubmed/27147095 http://dx.doi.org/10.1098/rspb.2015.3109 |
work_keys_str_mv | AT takeuchinobuto evolutionarilystabledisequilibriumendlessdynamicsofevolutioninastationarypopulation AT kanekokunihiko evolutionarilystabledisequilibriumendlessdynamicsofevolutioninastationarypopulation AT hogewegpaulien evolutionarilystabledisequilibriumendlessdynamicsofevolutioninastationarypopulation |