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Impact of Concanavalin-A-Mediated Cytoskeleton Disruption on Low-Density Lipoprotein Receptor-Related Protein-1 Internalization and Cell Surface Expression in Glioblastomas

The low-density lipoprotein receptor-related protein 1 (LRP-1) is a multiligand endocytic receptor, which plays a pivotal role in controlling cytoskeleton dynamics during cancer cell migration. Its rapid endocytosis further allows efficient clearance of extracellular ligands. Concanavalin-A (ConA) i...

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Detalles Bibliográficos
Autores principales: Nanni, Samuel Burke, Pratt, Jonathan, Beauchemin, David, Haidara, Khadidja, Annabi, Borhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874747/
https://www.ncbi.nlm.nih.gov/pubmed/27226736
http://dx.doi.org/10.4137/BIC.S38894