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Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response

OBJECTIVES: Three-dimensional organoids derived from primary pancreatic ductal adenocarcinomas are an attractive platform for testing potential anticancer drugs on patient-specific tissue. Optical metabolic imaging (OMI) is a novel tool used to assess drug-induced changes in cellular metabolism, and...

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Detalles Bibliográficos
Autores principales:	Walsh, Alex J., Castellanos, Jason A., Nagathihalli, Nagaraj S., Merchant, Nipun B., Skala, Melissa C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874911/ https://www.ncbi.nlm.nih.gov/pubmed/26495796 http://dx.doi.org/10.1097/MPA.0000000000000543

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