β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis

The Wnt/β-catenin pathway plays a central role in epidermal homeostasis and regeneration, but how it affects fibroblast fate decisions is unknown. We investigated the effect of targeted β-catenin stabilization in dermal fibroblasts. Comparative gene expression profiling of stem cell antigen 1(-) (Sc...

Descripción completa

Detalles Bibliográficos
Autores principales: Mastrogiannaki, Maria, Lichtenberger, Beate M., Reimer, Andreas, Collins, Charlotte A., Driskell, Ryan R., Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874948/
https://www.ncbi.nlm.nih.gov/pubmed/26902921
http://dx.doi.org/10.1016/j.jid.2016.01.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874948/
https://www.ncbi.nlm.nih.gov/pubmed/26902921
http://dx.doi.org/10.1016/j.jid.2016.01.036

Ejemplares similares