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β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis

The Wnt/β-catenin pathway plays a central role in epidermal homeostasis and regeneration, but how it affects fibroblast fate decisions is unknown. We investigated the effect of targeted β-catenin stabilization in dermal fibroblasts. Comparative gene expression profiling of stem cell antigen 1(-) (Sc...

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Detalles Bibliográficos
Autores principales:	Mastrogiannaki, Maria, Lichtenberger, Beate M., Reimer, Andreas, Collins, Charlotte A., Driskell, Ryan R., Watt, Fiona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874948/ https://www.ncbi.nlm.nih.gov/pubmed/26902921 http://dx.doi.org/10.1016/j.jid.2016.01.036

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