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New nsp8 isoform suggests mechanism for tuning viral RNA synthesis

During severe acute respiratory syndrome coronavirus (SARS-CoV) infection, the activity of the replication/transcription complexes (RTC) quickly peaks at 6 hours post infection (h.p.i) and then diminishes significantly in the late post-infection stages. This “down-up-down” regulation of RNA synthesi...

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Detalles Bibliográficos
Autores principales:	Li, Shuang, Zhao, Qi, Zhang, Yinjie, Zhang, Yang, Bartlam, Mark, Li, Xuemei, Rao, Zihe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875168/ https://www.ncbi.nlm.nih.gov/pubmed/21203988 http://dx.doi.org/10.1007/s13238-010-0028-8

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