Aurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients

High-Grade Serous Ovarian Carcinoma (HGSOC) is the predominant histotype of epithelial ovarian cancer (EOC), characterized by advanced stage at diagnosis, frequent TP53 mutation, rapid progression, and high responsiveness to platinum-based-chemotherapy. To date, standard first-line-chemotherapy in a...

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Detalles Bibliográficos
Autores principales: Mignogna, Chiara, Staropoli, Nicoletta, Botta, Cirino, De Marco, Carmela, Rizzuto, Antonia, Morelli, Michele, Di Cello, Annalisa, Franco, Renato, Camastra, Caterina, Presta, Ivan, Malara, Natalia, Salvino, Angela, Tassone, Pierfrancesco, Tagliaferri, Pierosandro, Barni, Tullio, Donato, Giuseppe, Di Vito, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875597/
https://www.ncbi.nlm.nih.gov/pubmed/27209210
http://dx.doi.org/10.1186/s13048-016-0238-7

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