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Influence of mTOR-inhibitors and mycophenolic acid on human cholangiocellular carcinoma and cancer associated fibroblasts
BACKGROUND: The incidence of Cholangiocellular Carcinoma (CCA) is increasing in the western world. The tumour has a high proportion of desmoplastic stroma and is correlated with a worse prognosis when cancer associated myofibroblasts (CAFs) are present. Recent studies showed promising results after...
Autores principales: | Heits, Nils, Heinze, Tillmann, Bernsmeier, Alexander, Kerber, Jannik, Hauser, Charlotte, Becker, Thomas, Kalthoff, Holger, Egberts, Jan-Hendrik, Braun, Felix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875636/ https://www.ncbi.nlm.nih.gov/pubmed/27206490 http://dx.doi.org/10.1186/s12885-016-2360-8 |
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