In vivo analysis of the effect of panobinostat on cell-associated HIV RNA and DNA levels and latent HIV infection

BACKGROUND: The latent reservoir in resting CD4(+) T cells presents a major barrier to HIV cure. Latency-reversing agents are therefore being developed with the ultimate goal of disrupting the latent state, resulting in induction of HIV expression and clearance of infected cells. Histone deacetylase...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Perry, Wu, Guoxin, Baker, Caroline E., Thayer, William O., Spagnuolo, Rae Ann, Sanchez, Rosa, Barrett, Stephanie, Howell, Bonnie, Margolis, David, Hazuda, Daria J., Archin, Nancie M., Garcia, J. Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875645/
https://www.ncbi.nlm.nih.gov/pubmed/27206407
http://dx.doi.org/10.1186/s12977-016-0268-7

Ejemplares similares

Ejemplares similares