Complement system activation contributes to the ependymal damage induced by microbial neuraminidase

BACKGROUND: In the rat brain, a single intracerebroventricular injection of neuraminidase from Clostridium perfringens induces ependymal detachment and death. This injury occurs before the infiltration of inflammatory blood cells; some reports implicate the complement system as a cause of these inju...

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Detalles Bibliográficos
Autores principales: Granados-Durán, Pablo, López-Ávalos, María Dolores, Hughes, Timothy R., Johnson, Krista, Morgan, B. Paul, Tamburini, Paul P., Fernández-Llebrez, Pedro, Grondona, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875702/
https://www.ncbi.nlm.nih.gov/pubmed/27209022
http://dx.doi.org/10.1186/s12974-016-0576-9

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