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Activation of chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712 by ethanol shock: insights from the promoter fusion studies

BACKGROUND: Streptomyces venezuelae ATCC 10712 produces antibiotics chloramphenicol (Cml) and jadomycin (Jad) in response to nutrient limitation and ethanol shock (ES), respectively. Biosynthesis of Cml and Jad was shown to be reciprocally regulated via the action of regulatory proteins JadR1 and Ja...

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Detalles Bibliográficos
Autores principales:	Sekurova, Olga N., Zhang, Jianhai, Kristiansen, Kåre A., Zotchev, Sergey B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875748/ https://www.ncbi.nlm.nih.gov/pubmed/27206520 http://dx.doi.org/10.1186/s12934-016-0484-9

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