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Randomized Comparative Bioavailability of a Novel Three-Dimensional Printed Fast-Melt Formulation of Levetiracetam Following the Administration of a Single 1000-mg Dose to Healthy Human Volunteers Under Fasting and Fed Conditions

BACKGROUND: Rapidly disintegrating or ‘fast-melt’ oral formulations have been developed recently to facilitate drug intake among patients. Even though these formulations have helped to improve therapy adherence, some of their limitations include: the dissolution time, their facility to be swallowed,...

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Detalles Bibliográficos
Autores principales: Boudriau, Sophie, Hanzel, Cecilia, Massicotte, Julie, Sayegh, Laura, Wang, Jing, Lefebvre, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875927/
https://www.ncbi.nlm.nih.gov/pubmed/27028750
http://dx.doi.org/10.1007/s40268-016-0132-1