Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients

BACKGROUND AND OBJECTIVE: Morphine dosing can be challenging in terminally ill adult patients due to the heterogeneous nature of the population and the difficulty of accurately assessing pain during sedation. To determine the pharmacokinetics of morphine, morphine-3-glucuronide (M3G) and morphine-6-...

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Detalles Bibliográficos
Autores principales: Franken, Linda G., Masman, Anniek D., de Winter, Brenda C. M., Koch, Birgit C. P., Baar, Frans P. M., Tibboel, Dick, van Gelder, Teun, Mathot, Ron A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875954/
https://www.ncbi.nlm.nih.gov/pubmed/26715216
http://dx.doi.org/10.1007/s40262-015-0345-4

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