Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change

Our presentation illustrates a rare case of primary renal pelvis malignant melanoma in a 35-year-old man. The diagnosis of malignant melanoma was based on immunophenotype and the detection of intracellular melanin pigment. The renal origin was proven by the presence of scattered melanocytes within t...

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Detalles Bibliográficos
Autores principales: Liapis, George, Sarlanis, Helen, Poulaki, Elpida, Stravodimos, Konstandinos, Riccioni, Olga, Lazaris, Andreas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876004/
https://www.ncbi.nlm.nih.gov/pubmed/27226943
http://dx.doi.org/10.7759/cureus.583
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author Liapis, George
Sarlanis, Helen
Poulaki, Elpida
Stravodimos, Konstandinos
Riccioni, Olga
Lazaris, Andreas C
author_facet Liapis, George
Sarlanis, Helen
Poulaki, Elpida
Stravodimos, Konstandinos
Riccioni, Olga
Lazaris, Andreas C
author_sort Liapis, George
collection PubMed
description Our presentation illustrates a rare case of primary renal pelvis malignant melanoma in a 35-year-old man. The diagnosis of malignant melanoma was based on immunophenotype and the detection of intracellular melanin pigment. The renal origin was proven by the presence of scattered melanocytes within the urothelium of the pelvis. The tumor exhibited extensive clear cell change that closely mimics clear cell renal cell carcinoma. The patient’s clinical history did not disclose any signs of previous melanocytic skin or mucosa lesions. Differential diagnosis includes tumors capable of synthesizing melanin or expressing melanocytic markers.
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spelling pubmed-48760042016-05-25 Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change Liapis, George Sarlanis, Helen Poulaki, Elpida Stravodimos, Konstandinos Riccioni, Olga Lazaris, Andreas C Cureus Pathology Our presentation illustrates a rare case of primary renal pelvis malignant melanoma in a 35-year-old man. The diagnosis of malignant melanoma was based on immunophenotype and the detection of intracellular melanin pigment. The renal origin was proven by the presence of scattered melanocytes within the urothelium of the pelvis. The tumor exhibited extensive clear cell change that closely mimics clear cell renal cell carcinoma. The patient’s clinical history did not disclose any signs of previous melanocytic skin or mucosa lesions. Differential diagnosis includes tumors capable of synthesizing melanin or expressing melanocytic markers. Cureus 2016-04-21 /pmc/articles/PMC4876004/ /pubmed/27226943 http://dx.doi.org/10.7759/cureus.583 Text en Copyright © 2016, Liapis et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Liapis, George
Sarlanis, Helen
Poulaki, Elpida
Stravodimos, Konstandinos
Riccioni, Olga
Lazaris, Andreas C
Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change
title Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change
title_full Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change
title_fullStr Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change
title_full_unstemmed Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change
title_short Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change
title_sort primary malignant melanoma of renal pelvis with extensive clear cell change
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876004/
https://www.ncbi.nlm.nih.gov/pubmed/27226943
http://dx.doi.org/10.7759/cureus.583
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