Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode

A novel electrochemical sensing approach, based on electropolymerization of a molecularly imprinted polypyrrole (MIPpy) film onto a glassy carbon electrode (GCE) surface, was developed for the detection of flunixin (FXN). The sensing conditions and the performance of the constructed sensor were asse...

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Detalles Bibliográficos
Autores principales: Radi, Abd-Elgawad, Abd El-Ghany, Nadia, Wahdan, Tarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876014/
https://www.ncbi.nlm.nih.gov/pubmed/27242945
http://dx.doi.org/10.1155/2016/5296582
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author Radi, Abd-Elgawad
Abd El-Ghany, Nadia
Wahdan, Tarek
author_facet Radi, Abd-Elgawad
Abd El-Ghany, Nadia
Wahdan, Tarek
author_sort Radi, Abd-Elgawad
collection PubMed
description A novel electrochemical sensing approach, based on electropolymerization of a molecularly imprinted polypyrrole (MIPpy) film onto a glassy carbon electrode (GCE) surface, was developed for the detection of flunixin (FXN). The sensing conditions and the performance of the constructed sensor were assessed by cyclic, differential pulse and (DPV) square wave voltammetry (SWV). The sensor exhibited high sensitivity, with linear responses in the range of 5.0 to 50.0 µM with detection limits of 1.5 and 1.0 µM for DPV and SWV, respectively. In addition, the sensor showed high selectivity towards FXN in comparison to other interferents. The sensor was successfully utilized for the direct determination of FXN in buffalo raw milk samples.
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spelling pubmed-48760142016-05-30 Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode Radi, Abd-Elgawad Abd El-Ghany, Nadia Wahdan, Tarek J Anal Methods Chem Research Article A novel electrochemical sensing approach, based on electropolymerization of a molecularly imprinted polypyrrole (MIPpy) film onto a glassy carbon electrode (GCE) surface, was developed for the detection of flunixin (FXN). The sensing conditions and the performance of the constructed sensor were assessed by cyclic, differential pulse and (DPV) square wave voltammetry (SWV). The sensor exhibited high sensitivity, with linear responses in the range of 5.0 to 50.0 µM with detection limits of 1.5 and 1.0 µM for DPV and SWV, respectively. In addition, the sensor showed high selectivity towards FXN in comparison to other interferents. The sensor was successfully utilized for the direct determination of FXN in buffalo raw milk samples. Hindawi Publishing Corporation 2016 2016-05-08 /pmc/articles/PMC4876014/ /pubmed/27242945 http://dx.doi.org/10.1155/2016/5296582 Text en Copyright © 2016 Abd-Elgawad Radi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Radi, Abd-Elgawad
Abd El-Ghany, Nadia
Wahdan, Tarek
Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode
title Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode
title_full Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode
title_fullStr Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode
title_full_unstemmed Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode
title_short Voltammetric Determination of Flunixin on Molecularly Imprinted Polypyrrole Modified Glassy Carbon Electrode
title_sort voltammetric determination of flunixin on molecularly imprinted polypyrrole modified glassy carbon electrode
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876014/
https://www.ncbi.nlm.nih.gov/pubmed/27242945
http://dx.doi.org/10.1155/2016/5296582
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AT wahdantarek voltammetricdeterminationofflunixinonmolecularlyimprintedpolypyrrolemodifiedglassycarbonelectrode

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