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Pathophysiology of hypophosphatasia and the potential role of asfotase alfa
Hypophosphatasia (HPP) is an inherited systemic bone disease that is characterized by bone hypomineralization. HPP is classified into six forms according to the age of onset and severity as perinatal (lethal), perinatal benign, infantile, childhood, adult, and odontohypophosphatasia. The causative g...
Autor principal: | Orimo, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876073/ https://www.ncbi.nlm.nih.gov/pubmed/27274262 http://dx.doi.org/10.2147/TCRM.S87956 |
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