The independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and the metabolism of atorvastatin

To evaluate the independent contribution of miRNAs to the missing heritability in CYP3A4/5 functionality and atorvastatin metabolism, the relationships among three levels of factors, namely (1) clinical characteristics, CYP3A4/5 genotypes, and miRNAs, (2) CYP3A4 and CYP3A5 mRNAs, and (3) CYP3A activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ju-E, Ren, Bin, Tang, Lan, Tang, Qian-Jie, Liu, Xiao-Ying, Li, Xin, Bai, Xue, Zhong, Wan-Ping, Meng, Jin-Xiu, Lin, Hao-Ming, Wu, Hong, Chen, Ji-Yan, Zhong, Shi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876377/
https://www.ncbi.nlm.nih.gov/pubmed/27211076
http://dx.doi.org/10.1038/srep26544

Ejemplares similares

Ejemplares similares