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Two-Photon Enzymatic Probes Visualizing Sub-cellular/Deep-brain Caspase Activities in Neurodegenerative Models

Caspases work as a double-edged sword in maintaining cell homeostasis. Highly regulated caspase activities are essential during animal development, but dysregulation might lead to different diseases, e.g. extreme caspase activation is known to promote neurodegeneration. At present, visualization of...

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Detalles Bibliográficos
Autores principales: Qian, Linghui, Zhang, Cheng-Wu, Mao, Yanli, Li, Lin, Gao, Nengyue, Lim, Kah-Leong, Xu, Qing-Hua, Yao, Shao Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876444/
https://www.ncbi.nlm.nih.gov/pubmed/27210613
http://dx.doi.org/10.1038/srep26385