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Two-Photon Enzymatic Probes Visualizing Sub-cellular/Deep-brain Caspase Activities in Neurodegenerative Models
Caspases work as a double-edged sword in maintaining cell homeostasis. Highly regulated caspase activities are essential during animal development, but dysregulation might lead to different diseases, e.g. extreme caspase activation is known to promote neurodegeneration. At present, visualization of...
Autores principales: | Qian, Linghui, Zhang, Cheng-Wu, Mao, Yanli, Li, Lin, Gao, Nengyue, Lim, Kah-Leong, Xu, Qing-Hua, Yao, Shao Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876444/ https://www.ncbi.nlm.nih.gov/pubmed/27210613 http://dx.doi.org/10.1038/srep26385 |
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