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CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver

Natural killer cells (NK) are highly enriched in the human liver, where they can regulate immunity and immunopathology. We probed them for a liver-resident subset, distinct from conventional bone-marrow-derived NK. CXCR6+ NK were strikingly enriched in healthy and diseased liver compared to blood (p...

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Detalles Bibliográficos
Autores principales: Stegmann, Kerstin A., Robertson, Francis, Hansi, Navjyot, Gill, Upkar, Pallant, Celeste, Christophides, Theodoros, Pallett, Laura J., Peppa, Dimitra, Dunn, Claire, Fusai, Giuseppe, Male, Victoria, Davidson, Brian R., Kennedy, Patrick, Maini, Mala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876507/
https://www.ncbi.nlm.nih.gov/pubmed/27210614
http://dx.doi.org/10.1038/srep26157