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Dendritic Polymers for Theranostics
Dendritic polymers are highly branched polymers with controllable structures, which possess a large population of terminal functional groups, low solution or melt viscosity, and good solubility. Their size, degree of branching and functionality can be adjusted and controlled through the synthetic pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876620/ https://www.ncbi.nlm.nih.gov/pubmed/27217829 http://dx.doi.org/10.7150/thno.14855 |
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author | Ma, Yuan Mou, Quanbing Wang, Dali Zhu, Xinyuan Yan, Deyue |
author_facet | Ma, Yuan Mou, Quanbing Wang, Dali Zhu, Xinyuan Yan, Deyue |
author_sort | Ma, Yuan |
collection | PubMed |
description | Dendritic polymers are highly branched polymers with controllable structures, which possess a large population of terminal functional groups, low solution or melt viscosity, and good solubility. Their size, degree of branching and functionality can be adjusted and controlled through the synthetic procedures. These tunable structures correspond to application-related properties, such as biodegradability, biocompatibility, stimuli-responsiveness and self-assembly ability, which are the key points for theranostic applications, including chemotherapeutic theranostics, biotherapeutic theranostics, phototherapeutic theranostics, radiotherapeutic theranostics and combined therapeutic theranostics. Up to now, significant progress has been made for the dendritic polymers in solving some of the fundamental and technical questions toward their theranostic applications. In this review, we briefly summarize how to control the structures of dendritic polymers, the theranostics-related properties derived from their structures and their theranostics-related applications. |
format | Online Article Text |
id | pubmed-4876620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-48766202016-05-23 Dendritic Polymers for Theranostics Ma, Yuan Mou, Quanbing Wang, Dali Zhu, Xinyuan Yan, Deyue Theranostics Review Dendritic polymers are highly branched polymers with controllable structures, which possess a large population of terminal functional groups, low solution or melt viscosity, and good solubility. Their size, degree of branching and functionality can be adjusted and controlled through the synthetic procedures. These tunable structures correspond to application-related properties, such as biodegradability, biocompatibility, stimuli-responsiveness and self-assembly ability, which are the key points for theranostic applications, including chemotherapeutic theranostics, biotherapeutic theranostics, phototherapeutic theranostics, radiotherapeutic theranostics and combined therapeutic theranostics. Up to now, significant progress has been made for the dendritic polymers in solving some of the fundamental and technical questions toward their theranostic applications. In this review, we briefly summarize how to control the structures of dendritic polymers, the theranostics-related properties derived from their structures and their theranostics-related applications. Ivyspring International Publisher 2016-04-27 /pmc/articles/PMC4876620/ /pubmed/27217829 http://dx.doi.org/10.7150/thno.14855 Text en © Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See http://ivyspring.com/terms for terms and conditions. |
spellingShingle | Review Ma, Yuan Mou, Quanbing Wang, Dali Zhu, Xinyuan Yan, Deyue Dendritic Polymers for Theranostics |
title | Dendritic Polymers for Theranostics |
title_full | Dendritic Polymers for Theranostics |
title_fullStr | Dendritic Polymers for Theranostics |
title_full_unstemmed | Dendritic Polymers for Theranostics |
title_short | Dendritic Polymers for Theranostics |
title_sort | dendritic polymers for theranostics |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876620/ https://www.ncbi.nlm.nih.gov/pubmed/27217829 http://dx.doi.org/10.7150/thno.14855 |
work_keys_str_mv | AT mayuan dendriticpolymersfortheranostics AT mouquanbing dendriticpolymersfortheranostics AT wangdali dendriticpolymersfortheranostics AT zhuxinyuan dendriticpolymersfortheranostics AT yandeyue dendriticpolymersfortheranostics |