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Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds

A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as antitrypanosomatid agents. All tested compounds were active or moderately active against Trypanosoma cruzi amastigotes in infected L6 c...

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Detalles Bibliográficos
Autores principales:	Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Szular, Joanna, Kaiser, Marcel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editions Scientifiques Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876673/ https://www.ncbi.nlm.nih.gov/pubmed/27092415 http://dx.doi.org/10.1016/j.ejmech.2016.04.010

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