A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor confers resistance to spinosad in Drosophila melanogaster

Spinosad, a widely used and economically important insecticide, targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Several studies have associated loss of function mutations in the insect nAChR α6 subunit with resistance to spinosad, and in the process identified thi...

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Detalles Bibliográficos
Autores principales: Zimmer, Christoph T., Garrood, William T., Puinean, A. Mirel, Eckel-Zimmer, Manuela, Williamson, Martin S., Davies, T.G. Emyr, Bass, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876769/
https://www.ncbi.nlm.nih.gov/pubmed/27117524
http://dx.doi.org/10.1016/j.ibmb.2016.04.007

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