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Insulin Dose and Cardiovascular Mortality in the ACCORD Trial

OBJECTIVE: In the ACCORD trial, intensive treatment of patients with type 2 diabetes and high cardiovascular (CV) risk was associated with higher all-cause and CV mortality. Post hoc analyses have failed to implicate rapid reduction of glucose, hypoglycemia, or specific drugs as the causes of this f...

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Detalles Bibliográficos
Autores principales: Siraj, Elias S., Rubin, Daniel J., Riddle, Matthew C., Miller, Michael E., Hsu, Fang-Chi, Ismail-Beigi, Faramarz, Chen, Shyh-Huei, Ambrosius, Walter T., Thomas, Abraham, Bestermann, William, Buse, John B., Genuth, Saul, Joyce, Carol, Kovacs, Christopher S., O'Connor, Patrick J., Sigal, Ronald J., Solomon, Sol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876773/
https://www.ncbi.nlm.nih.gov/pubmed/26464212
http://dx.doi.org/10.2337/dc15-0598