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Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling

Mitochondrial ADP transport may represent a convergence point unifying two prominent working models for the development of insulin resistance, as reactive lipids (specifically palmitoyl-CoA [P-CoA]) can inhibit ADP transport and subsequently increase mitochondrial reactive oxygen species emissions....

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Detalles Bibliográficos
Autores principales: Ludzki, Alison, Paglialunga, Sabina, Smith, Brennan K., Herbst, Eric A.F., Allison, Mary K., Heigenhauser, George J., Neufer, P. Darrell, Holloway, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876790/
https://www.ncbi.nlm.nih.gov/pubmed/25845660
http://dx.doi.org/10.2337/db14-1838

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