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Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling
Mitochondrial ADP transport may represent a convergence point unifying two prominent working models for the development of insulin resistance, as reactive lipids (specifically palmitoyl-CoA [P-CoA]) can inhibit ADP transport and subsequently increase mitochondrial reactive oxygen species emissions....
Autores principales: | Ludzki, Alison, Paglialunga, Sabina, Smith, Brennan K., Herbst, Eric A.F., Allison, Mary K., Heigenhauser, George J., Neufer, P. Darrell, Holloway, Graham P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876790/ https://www.ncbi.nlm.nih.gov/pubmed/25845660 http://dx.doi.org/10.2337/db14-1838 |
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