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Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?

The need for effective treatments halting Alzheimer's disease (AD) urges the discovery of the earliest possible biomarkers. Agrin is increased in the early stages of AD and is involved in amyloid-β (Aβ) fibrillation and synaptogenesis. We investigated the potential of agrin as an early AD cereb...

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Detalles Bibliográficos
Autores principales: Del Campo Milan, Marta, Zuroff, Leah, Jimenez, Connie R., Scheltens, Philip, Teunissen, Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876904/
https://www.ncbi.nlm.nih.gov/pubmed/27239494
http://dx.doi.org/10.1016/j.dadm.2014.11.008