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Regulation of aldosterone secretion by Ca(v)1.3
Aldosterone-producing adenomas (APAs) vary in phenotype and genotype. Zona glomerulosa (ZG)-like APAs frequently have mutations of an L-type calcium channel (LTCC) Ca(V)1.3. Using a novel antagonist of Ca(V)1.3, compound 8, we investigated the role of Ca(V)1.3 on steroidogenesis in the human adrenoc...
Autores principales: | Xie, Catherine B., Haris Shaikh, Lalarukh, Garg, Sumedha, Tanriver, Gizem, Teo, Ada E. D., Zhou, Junhua, Maniero, Carmela, Zhao, Wanfeng, Kang, Soosung, Silverman, Richard B., Azizan, Elena A. B., Brown, Morris J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876952/ https://www.ncbi.nlm.nih.gov/pubmed/27098837 http://dx.doi.org/10.1038/srep24697 |
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