Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15

We describe a stromal predominant Wilms tumor with focal anaplasia and a complex, tumor specific chromosome 11 aberration: a homozygous deletion of the entire WT1 gene within a heterozygous 11p13 deletion and an additional region of uniparental disomy (UPD) limited to 11p15.5-p15.2 including the IGF...

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Detalles Bibliográficos
Autores principales: Brandt, Artur, Löhers, Katharina, Beier, Manfred, Leube, Barbara, de Torres, Carmen, Mora, Jaume, Arora, Parineeta, Jat, Parmjit S., Royer-Pokora, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876997/
https://www.ncbi.nlm.nih.gov/pubmed/27213811
http://dx.doi.org/10.1371/journal.pone.0155561

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