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Cholesterol Corrects Altered Conformation of MHC-II Protein in Leishmania donovani Infected Macrophages: Implication in Therapy

BACKGROUND: Previously we reported that Kala-azar patients show progressive decrease in serum cholesterol as a function of splenic parasite burden. Splenic macrophages (MΦ) of Leishmania donovani (LD) infected mice show decrease in membrane cholesterol, while LD infected macrophages (I-MΦ) show defe...

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Detalles Bibliográficos
Autores principales:	Roy, Koushik, Mandloi, Sapan, Chakrabarti, Saikat, Roy, Syamal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877013/ https://www.ncbi.nlm.nih.gov/pubmed/27214205 http://dx.doi.org/10.1371/journal.pntd.0004710

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