The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination

Growth factors of the gp130 family promote oligodendrocyte differentiation, and viability, and myelination, but their mechanisms of action are incompletely understood. Here, we show that these effects are coordinated, in part, by the transcriptional activator Krüppel-like factor-6 (Klf6). Klf6 is ra...

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Detalles Bibliográficos
Autores principales: Laitman, Benjamin M., Asp, Linnéa, Mariani, John N., Zhang, Jingya, Liu, Jia, Sawai, Setsu, Chapouly, Candice, Horng, Sam, Kramer, Elisabeth G., Mitiku, Nesanet, Loo, Hannah, Burlant, Natalie, Pedre, Xiomara, Hara, Yuko, Nudelman, German, Zaslavsky, Elena, Lee, Young-Min, Braun, David A., Lu, Q. Richard, Narla, Goutham, Raine, Cedric S., Friedman, Scott L., Casaccia, Patrizia, John, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877075/
https://www.ncbi.nlm.nih.gov/pubmed/27213272
http://dx.doi.org/10.1371/journal.pbio.1002467

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