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Precision-Cut Kidney Slices as a Tool to Understand the Dynamics of Extracellular Matrix Remodeling in Renal Fibrosis

The aim of this study was to set up an ex vivo model for renal interstitial fibrosis in order to investigate the extracellular matrix (ECM) turnover profile in the fibrotic kidney. We induced kidney fibrosis in fourteen 12-week-old male Sprague Dawley rats by unilateral ureteral obstruction (UUO) su...

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Detalles Bibliográficos
Autores principales:	Genovese, Federica, Kàrpàti, Zsolt S., Nielsen, Signe H., Karsdal, Morten A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877083/ https://www.ncbi.nlm.nih.gov/pubmed/27257368 http://dx.doi.org/10.4137/BMI.S38439

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