IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling

Microvascular leakage due to endothelial barrier dysfunction is a prominent feature of T helper 2 (Th2) cytokine mediated allergic inflammation. Interleukin-4 (IL-4) is a potent Th2 cytokine, known to impair the barrier function of endothelial cells. However, the effectors mediating IL-4 induced cyt...

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Detalles Bibliográficos
Autores principales: Skaria, Tom, Burgener, Julia, Bachli, Esther, Schoedon, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877093/
https://www.ncbi.nlm.nih.gov/pubmed/27214384
http://dx.doi.org/10.1371/journal.pone.0156002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877093/
https://www.ncbi.nlm.nih.gov/pubmed/27214384
http://dx.doi.org/10.1371/journal.pone.0156002

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