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IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling
Microvascular leakage due to endothelial barrier dysfunction is a prominent feature of T helper 2 (Th2) cytokine mediated allergic inflammation. Interleukin-4 (IL-4) is a potent Th2 cytokine, known to impair the barrier function of endothelial cells. However, the effectors mediating IL-4 induced cyt...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877093/ https://www.ncbi.nlm.nih.gov/pubmed/27214384 http://dx.doi.org/10.1371/journal.pone.0156002 |