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Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis

OBJECTIVE: assess the adherence levels to antiretroviral therapy in people coinfected with HIV/tuberculosis and correlate these levels with the sociodemographic and clinical variables of the study population. METHOD: cross-sectional study involving 74 male and female adults coinfected with HIV/tuber...

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Detalles Bibliográficos
Autores principales: Lemos, Larissa de Araújo, Fiuza, Maria Luciana Teles, Reis, Renata Karina, Ferrer, André Carvalho, Gir, Elucir, Galvão, Marli Teresinha Gimeniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877141/
https://www.ncbi.nlm.nih.gov/pubmed/27192416
http://dx.doi.org/10.1590/1518-8345.0537.2691
Descripción
Sumario:OBJECTIVE: assess the adherence levels to antiretroviral therapy in people coinfected with HIV/tuberculosis and correlate these levels with the sociodemographic and clinical variables of the study population. METHOD: cross-sectional study involving 74 male and female adults coinfected with HIV/tuberculosis. For the data collection, a sociodemographic and clinical assessment form and the Antiretroviral Treatment Adherence Assessment Questionnaire were used. For the data analysis, the software STATA version 11 was used, through descriptive statistics, Fisher's chi-square exact test and the probability test. RESULTS: men were predominant (79.7%), between 30 and 39 years of age (35.1%), low income (75.7%) and pulmonary tuberculosis (71.6%). Adherence to antiretroviral therapy was inappropriate in 78.1% of the men; 61.0% of single people; 47.0% unemployed and 76.5% among people gaining less than one minimum wage. A significant difference was observed between compliance and length of use of antiretrovirals (p=0.018), sexual orientation (p=0.024) and number of children (p=0.029). CONCLUSION: the coinfected patients presented inappropriate adherence to the antiretrovirals, a fact that negatively affects the health conditions of the people living with HIV/tuberculosis coinfection. A statistically significant correlation was found between the levels of adherence and some sociodemographic and clinical characteristics.