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Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis

OBJECTIVE: assess the adherence levels to antiretroviral therapy in people coinfected with HIV/tuberculosis and correlate these levels with the sociodemographic and clinical variables of the study population. METHOD: cross-sectional study involving 74 male and female adults coinfected with HIV/tuber...

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Autores principales: Lemos, Larissa de Araújo, Fiuza, Maria Luciana Teles, Reis, Renata Karina, Ferrer, André Carvalho, Gir, Elucir, Galvão, Marli Teresinha Gimeniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877141/
https://www.ncbi.nlm.nih.gov/pubmed/27192416
http://dx.doi.org/10.1590/1518-8345.0537.2691
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author Lemos, Larissa de Araújo
Fiuza, Maria Luciana Teles
Reis, Renata Karina
Ferrer, André Carvalho
Gir, Elucir
Galvão, Marli Teresinha Gimeniz
author_facet Lemos, Larissa de Araújo
Fiuza, Maria Luciana Teles
Reis, Renata Karina
Ferrer, André Carvalho
Gir, Elucir
Galvão, Marli Teresinha Gimeniz
author_sort Lemos, Larissa de Araújo
collection PubMed
description OBJECTIVE: assess the adherence levels to antiretroviral therapy in people coinfected with HIV/tuberculosis and correlate these levels with the sociodemographic and clinical variables of the study population. METHOD: cross-sectional study involving 74 male and female adults coinfected with HIV/tuberculosis. For the data collection, a sociodemographic and clinical assessment form and the Antiretroviral Treatment Adherence Assessment Questionnaire were used. For the data analysis, the software STATA version 11 was used, through descriptive statistics, Fisher's chi-square exact test and the probability test. RESULTS: men were predominant (79.7%), between 30 and 39 years of age (35.1%), low income (75.7%) and pulmonary tuberculosis (71.6%). Adherence to antiretroviral therapy was inappropriate in 78.1% of the men; 61.0% of single people; 47.0% unemployed and 76.5% among people gaining less than one minimum wage. A significant difference was observed between compliance and length of use of antiretrovirals (p=0.018), sexual orientation (p=0.024) and number of children (p=0.029). CONCLUSION: the coinfected patients presented inappropriate adherence to the antiretrovirals, a fact that negatively affects the health conditions of the people living with HIV/tuberculosis coinfection. A statistically significant correlation was found between the levels of adherence and some sociodemographic and clinical characteristics.
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spelling pubmed-48771412016-06-01 Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis Lemos, Larissa de Araújo Fiuza, Maria Luciana Teles Reis, Renata Karina Ferrer, André Carvalho Gir, Elucir Galvão, Marli Teresinha Gimeniz Rev Lat Am Enfermagem Original Articles OBJECTIVE: assess the adherence levels to antiretroviral therapy in people coinfected with HIV/tuberculosis and correlate these levels with the sociodemographic and clinical variables of the study population. METHOD: cross-sectional study involving 74 male and female adults coinfected with HIV/tuberculosis. For the data collection, a sociodemographic and clinical assessment form and the Antiretroviral Treatment Adherence Assessment Questionnaire were used. For the data analysis, the software STATA version 11 was used, through descriptive statistics, Fisher's chi-square exact test and the probability test. RESULTS: men were predominant (79.7%), between 30 and 39 years of age (35.1%), low income (75.7%) and pulmonary tuberculosis (71.6%). Adherence to antiretroviral therapy was inappropriate in 78.1% of the men; 61.0% of single people; 47.0% unemployed and 76.5% among people gaining less than one minimum wage. A significant difference was observed between compliance and length of use of antiretrovirals (p=0.018), sexual orientation (p=0.024) and number of children (p=0.029). CONCLUSION: the coinfected patients presented inappropriate adherence to the antiretrovirals, a fact that negatively affects the health conditions of the people living with HIV/tuberculosis coinfection. A statistically significant correlation was found between the levels of adherence and some sociodemographic and clinical characteristics. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2016-05-17 /pmc/articles/PMC4877141/ /pubmed/27192416 http://dx.doi.org/10.1590/1518-8345.0537.2691 Text en http://creativecommons.org/licenses/by/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Articles
Lemos, Larissa de Araújo
Fiuza, Maria Luciana Teles
Reis, Renata Karina
Ferrer, André Carvalho
Gir, Elucir
Galvão, Marli Teresinha Gimeniz
Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
title Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
title_full Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
title_fullStr Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
title_full_unstemmed Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
title_short Adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
title_sort adherence to antiretrovirals in people coinfected with the human immunodeficiency virus and tuberculosis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877141/
https://www.ncbi.nlm.nih.gov/pubmed/27192416
http://dx.doi.org/10.1590/1518-8345.0537.2691
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