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Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing

BACKGROUND: Frailty is a state of increased vulnerability to poor resolution of homeostasis after a stressor event, which increases the risk of adverse outcomes including falls, disability and death. The underlying pathophysiological pathways of frailty are not known but the hypothalamic–pituitary–a...

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Detalles Bibliográficos
Autores principales: Mekli, Krisztina, Nazroo, James Y., Marshall, Alan D., Kumari, Meena, Pendleton, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877432/
https://www.ncbi.nlm.nih.gov/pubmed/26248682
http://dx.doi.org/10.1007/s40520-015-0419-z