Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus

Morvan syndrome (MoS) is a rare paraneoplastic autoimmune disorder characterized by peripheral nerve hyperexcitability, autonomic dysfunction, and sleep disorders. Systemic lupus erythmatosus (SLE) cooccurs in 6–10% of patients with thymoma. It may occur before, concurrently with, or after thymoma d...

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Detalles Bibliográficos
Autores principales: Macaron, Gabrielle, El Rassy, Elie, Koussa, Salam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877454/
https://www.ncbi.nlm.nih.gov/pubmed/27247812
http://dx.doi.org/10.1155/2016/9142486
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author Macaron, Gabrielle
El Rassy, Elie
Koussa, Salam
author_facet Macaron, Gabrielle
El Rassy, Elie
Koussa, Salam
author_sort Macaron, Gabrielle
collection PubMed
description Morvan syndrome (MoS) is a rare paraneoplastic autoimmune disorder characterized by peripheral nerve hyperexcitability, autonomic dysfunction, and sleep disorders. Systemic lupus erythmatosus (SLE) cooccurs in 6–10% of patients with thymoma. It may occur before, concurrently with, or after thymoma diagnosis. This paper reports the first case of cooccurrence of SLE, thymic carcinoma, and MoS. The cooccurrence of SLE, thymoma, and MoS delineates the generalized autoimmunity process. Symptoms of both MoS and SLE abated upon tumor resection.
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spelling pubmed-48774542016-05-31 Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus Macaron, Gabrielle El Rassy, Elie Koussa, Salam Case Rep Neurol Med Case Report Morvan syndrome (MoS) is a rare paraneoplastic autoimmune disorder characterized by peripheral nerve hyperexcitability, autonomic dysfunction, and sleep disorders. Systemic lupus erythmatosus (SLE) cooccurs in 6–10% of patients with thymoma. It may occur before, concurrently with, or after thymoma diagnosis. This paper reports the first case of cooccurrence of SLE, thymic carcinoma, and MoS. The cooccurrence of SLE, thymoma, and MoS delineates the generalized autoimmunity process. Symptoms of both MoS and SLE abated upon tumor resection. Hindawi Publishing Corporation 2016 2016-05-10 /pmc/articles/PMC4877454/ /pubmed/27247812 http://dx.doi.org/10.1155/2016/9142486 Text en Copyright © 2016 Gabrielle Macaron et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Macaron, Gabrielle
El Rassy, Elie
Koussa, Salam
Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_full Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_fullStr Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_full_unstemmed Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_short Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_sort morvan syndrome secondary to thymic carcinoma in a patient with systemic lupus erythematosus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877454/
https://www.ncbi.nlm.nih.gov/pubmed/27247812
http://dx.doi.org/10.1155/2016/9142486
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AT koussasalam morvansyndromesecondarytothymiccarcinomainapatientwithsystemiclupuserythematosus

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