c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea123

Prevention of auditory hair cell death offers therapeutic potential to rescue hearing. Pharmacological blockade of JNK/c-Jun signaling attenuates injury-induced hair cell loss, but with unsolved mechanisms. We have characterized the c-Jun stress response in the mouse cochlea challenged with acoustic...

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Detalles Bibliográficos
Autores principales: Anttonen, Tommi, Herranen, Anni, Virkkala, Jussi, Kirjavainen, Anna, Elomaa, Pinja, Laos, Maarja, Liang, Xingqun, Ylikoski, Jukka, Behrens, Axel, Pirvola, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877566/
https://www.ncbi.nlm.nih.gov/pubmed/27257624
http://dx.doi.org/10.1523/ENEURO.0047-16.2016

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