Cold-inducible RNA-binding protein causes endothelial dysfunction via activation of Nlrp3 inflammasome

Cold-inducible RNA-binding protein (CIRP) is a damage-associated molecular pattern (DAMP) molecule which stimulates proinflammatory cytokine release in hemorrhage and sepsis. Under these medical conditions, disruption of endothelial homeostasis and barrier integrity, typically induced by proinflamma...

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Detalles Bibliográficos
Autores principales: Yang, Weng-Lang, Sharma, Archna, Wang, Zhimin, Li, Zhigang, Fan, Jie, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877585/
https://www.ncbi.nlm.nih.gov/pubmed/27217302
http://dx.doi.org/10.1038/srep26571

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