Mice lacking Programmed cell death-1 show a role for CD8(+) T cells in long-term immunity against blood-stage malaria

Even after years of experiencing malaria, caused by infection with Plasmodium species, individuals still have incomplete immunity and develop low-density parasitemia on re-infection. Previous studies using the P. chabaudi (Pch) mouse model to understand the reason for chronic malaria, found that mic...

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Detalles Bibliográficos
Autores principales: Horne-Debets, Joshua M., Karunarathne, Deshapriya S., Faleiro, Rebecca J., Poh, Chek Meng, Renia, Laurent, Wykes, Michelle N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877649/
https://www.ncbi.nlm.nih.gov/pubmed/27217330
http://dx.doi.org/10.1038/srep26210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877649/
https://www.ncbi.nlm.nih.gov/pubmed/27217330
http://dx.doi.org/10.1038/srep26210

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