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Mice lacking Programmed cell death-1 show a role for CD8(+) T cells in long-term immunity against blood-stage malaria
Even after years of experiencing malaria, caused by infection with Plasmodium species, individuals still have incomplete immunity and develop low-density parasitemia on re-infection. Previous studies using the P. chabaudi (Pch) mouse model to understand the reason for chronic malaria, found that mic...
Autores principales: | Horne-Debets, Joshua M., Karunarathne, Deshapriya S., Faleiro, Rebecca J., Poh, Chek Meng, Renia, Laurent, Wykes, Michelle N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877649/ https://www.ncbi.nlm.nih.gov/pubmed/27217330 http://dx.doi.org/10.1038/srep26210 |
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