Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2123

The activity-regulated cytoskeleton-associated (Arc) protein controls synaptic strength by facilitating AMPA receptor (AMPAR) endocytosis. Here we demonstrate that Arc targets AMPAR to be internalized through a direct interaction with the clathrin-adaptor protein 2 (AP-2). We show that Arc overexpre...

Descripción completa

Detalles Bibliográficos
Autores principales: DaSilva, Luis L. P., Wall, Mark J., P. de Almeida, Luciana, Wauters, Sandrine C., Januário, Yunan C., Müller, Jürgen, Corrêa, Sonia A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877669/
https://www.ncbi.nlm.nih.gov/pubmed/27257628
http://dx.doi.org/10.1523/ENEURO.0144-15.2016

Ejemplares similares

Ejemplares similares