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Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Hypoxia as a result of pulmonary tissue damage due to unresolved inflammation during invasive pulmonary aspergillosis (IPA) is associated with a poor outcome. Aspergillus fumigatus can exploit the hypoxic microenvironment in the lung, but the inflammatory response required for fungal clearance can b...
Autores principales: | Gresnigt, Mark S., Rekiki, Abdessalem, Rasid, Orhan, Savers, Amélie, Jouvion, Grégory, Dannaoui, Eric, Parlato, Marianna, Fitting, Catherine, Brock, Matthias, Cavaillon, Jean-Marc, van de Veerdonk, Frank L., Ibrahim-Granet, Oumaïma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877709/ https://www.ncbi.nlm.nih.gov/pubmed/27215684 http://dx.doi.org/10.1038/srep26490 |
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