Cargando…

Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation

PURPOSE: To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in pseudoexfoliation (PEX) syndrome and its diurnal variation. METHODS: In this prospective, non-comparative, interventional case series, phacoemulsification was done for patients with PEX and concomitant visually s...

Descripción completa

Detalles Bibliográficos
Autores principales: Vahedian, Zakieh, Salmanroghani, Roham, Fakhraie, Ghasem, Moghimi, Sasan, Eslami, Yadollah, Zarei, Reza, Mohammadi, Massood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877725/
https://www.ncbi.nlm.nih.gov/pubmed/27239568
http://dx.doi.org/10.1016/j.joco.2015.09.006
_version_ 1782433431802609664
author Vahedian, Zakieh
Salmanroghani, Roham
Fakhraie, Ghasem
Moghimi, Sasan
Eslami, Yadollah
Zarei, Reza
Mohammadi, Massood
author_facet Vahedian, Zakieh
Salmanroghani, Roham
Fakhraie, Ghasem
Moghimi, Sasan
Eslami, Yadollah
Zarei, Reza
Mohammadi, Massood
author_sort Vahedian, Zakieh
collection PubMed
description PURPOSE: To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in pseudoexfoliation (PEX) syndrome and its diurnal variation. METHODS: In this prospective, non-comparative, interventional case series, phacoemulsification was done for patients with PEX and concomitant visually significant cataract. Follow-up examinations including IOP measurement were done at postoperative day 1, week 1, month 1, month 3, and month 6. All IOP measurements were performed twice daily: once in the morning between 8 and 10 AM and the other in the evening between 6 and 8 PM. The minimum and maximum IOP and the mean IOP were recorded. IOP variation was defined as the difference between maximum and minimum pressures. RESULTS: Sixty-eight eyes of 68 patients were analyzed. The mean IOP dropped from 17.45 ± 3.32 mm Hg to 12.57 ± 1.58 mm Hg at 6 months. The minimum and maximum IOP dropped from 14.97 ± 3.46 mm Hg and 20.03 ± 3.39 to 11.53 ± 1.79 mm Hg and 13.01 ± 1.81 after 6 months, respectively. Diurnal IOP variation dropped from 5.06 ± 1.85 mm Hg (range 2–10) at baseline to 1.49 ± 0.93 mm Hg (range 0–4) at postoperative month 6 (p < 0.001 for all). This drop was not correlated with age and CCT, but was strongly correlated with baseline IOP variation (r = 0.847, p < 0.001). CONCLUSION: Phacoemulsification without any additional intervention can be an attractive choice in managing the IOP and its diurnal variations in pseudoexfoliation patients, even with elevated IOP, who do not have advanced optic nerve damage.
format Online
Article
Text
id pubmed-4877725
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-48777252016-05-27 Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation Vahedian, Zakieh Salmanroghani, Roham Fakhraie, Ghasem Moghimi, Sasan Eslami, Yadollah Zarei, Reza Mohammadi, Massood J Curr Ophthalmol Article PURPOSE: To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in pseudoexfoliation (PEX) syndrome and its diurnal variation. METHODS: In this prospective, non-comparative, interventional case series, phacoemulsification was done for patients with PEX and concomitant visually significant cataract. Follow-up examinations including IOP measurement were done at postoperative day 1, week 1, month 1, month 3, and month 6. All IOP measurements were performed twice daily: once in the morning between 8 and 10 AM and the other in the evening between 6 and 8 PM. The minimum and maximum IOP and the mean IOP were recorded. IOP variation was defined as the difference between maximum and minimum pressures. RESULTS: Sixty-eight eyes of 68 patients were analyzed. The mean IOP dropped from 17.45 ± 3.32 mm Hg to 12.57 ± 1.58 mm Hg at 6 months. The minimum and maximum IOP dropped from 14.97 ± 3.46 mm Hg and 20.03 ± 3.39 to 11.53 ± 1.79 mm Hg and 13.01 ± 1.81 after 6 months, respectively. Diurnal IOP variation dropped from 5.06 ± 1.85 mm Hg (range 2–10) at baseline to 1.49 ± 0.93 mm Hg (range 0–4) at postoperative month 6 (p < 0.001 for all). This drop was not correlated with age and CCT, but was strongly correlated with baseline IOP variation (r = 0.847, p < 0.001). CONCLUSION: Phacoemulsification without any additional intervention can be an attractive choice in managing the IOP and its diurnal variations in pseudoexfoliation patients, even with elevated IOP, who do not have advanced optic nerve damage. Elsevier 2015-11-25 /pmc/articles/PMC4877725/ /pubmed/27239568 http://dx.doi.org/10.1016/j.joco.2015.09.006 Text en © 2015 Iranian Society of Opthalmology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Vahedian, Zakieh
Salmanroghani, Roham
Fakhraie, Ghasem
Moghimi, Sasan
Eslami, Yadollah
Zarei, Reza
Mohammadi, Massood
Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation
title Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation
title_full Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation
title_fullStr Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation
title_full_unstemmed Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation
title_short Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure and its diurnal variation
title_sort pseudoexfoliation syndrome: effect of phacoemulsification on intraocular pressure and its diurnal variation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877725/
https://www.ncbi.nlm.nih.gov/pubmed/27239568
http://dx.doi.org/10.1016/j.joco.2015.09.006
work_keys_str_mv AT vahedianzakieh pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation
AT salmanroghaniroham pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation
AT fakhraieghasem pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation
AT moghimisasan pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation
AT eslamiyadollah pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation
AT zareireza pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation
AT mohammadimassood pseudoexfoliationsyndromeeffectofphacoemulsificationonintraocularpressureanditsdiurnalvariation