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Inhibition of CaMKIV relieves streptozotocin-induced diabetic neuropathic pain through regulation of HMGB1

BACKGROUND: The pathogenesis of diabetic neuropathic pain is complicated and its underlying mechanisms remain unclear. Calmodulin-dependent protein kinases (CaMKs) IV (CaMKIV), one of CaMKs, regulates several transcription factors in pain mechanisms. High-mobility group box 1 (HMGB1) is a key mediat...

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Detalles Bibliográficos
Autores principales:	Zhao, Xin, Shen, Le, Xu, Li, Wang, Zhiyao, Ma, Chao, Huang, Yuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877728/ https://www.ncbi.nlm.nih.gov/pubmed/27216039 http://dx.doi.org/10.1186/s12871-016-0191-4

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