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Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review

Pelvic actinomycosis comprises a rare, subacute to chronic bacterial infection characterised by suppurative and granulomatous inflammation. Diagnosis is difficult as it may simulate pelvic malignancies. Laboratory and radiological findings are non-specific. We reported on 2 cases of pelvic actinomyc...

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Autores principales: Laios, Alex, Terekh, Iryna, Majd, Hooman Soleymani, Pathiraja, Pubudu, Manek, Sanjiv, Haldar, Krishnayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877746/
https://www.ncbi.nlm.nih.gov/pubmed/27231558
http://dx.doi.org/10.1186/2053-6844-1-5
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author Laios, Alex
Terekh, Iryna
Majd, Hooman Soleymani
Pathiraja, Pubudu
Manek, Sanjiv
Haldar, Krishnayan
author_facet Laios, Alex
Terekh, Iryna
Majd, Hooman Soleymani
Pathiraja, Pubudu
Manek, Sanjiv
Haldar, Krishnayan
author_sort Laios, Alex
collection PubMed
description Pelvic actinomycosis comprises a rare, subacute to chronic bacterial infection characterised by suppurative and granulomatous inflammation. Diagnosis is difficult as it may simulate pelvic malignancies. Laboratory and radiological findings are non-specific. We reported on 2 cases of pelvic actinomycosis mimicking ovarian malignancy with different management approaches that lead to opposite outcomes. We reviewed the literature on pelvic actinomycosis imitating ovarian cancer with a focus on its surgical management. Despite agreement on the duration of antibiotic therapy following surgical management, consensus regarding surgical approach was rather equivocal. We concluded that pelvic actinomycosis should be strongly suspected in women with presumed ovarian cancer of atypical presentation and a history of intrauterine devices (IUD). ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/2053-6844-1-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-48777462016-05-26 Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review Laios, Alex Terekh, Iryna Majd, Hooman Soleymani Pathiraja, Pubudu Manek, Sanjiv Haldar, Krishnayan Gynecol Oncol Res Pract Case Report Pelvic actinomycosis comprises a rare, subacute to chronic bacterial infection characterised by suppurative and granulomatous inflammation. Diagnosis is difficult as it may simulate pelvic malignancies. Laboratory and radiological findings are non-specific. We reported on 2 cases of pelvic actinomycosis mimicking ovarian malignancy with different management approaches that lead to opposite outcomes. We reviewed the literature on pelvic actinomycosis imitating ovarian cancer with a focus on its surgical management. Despite agreement on the duration of antibiotic therapy following surgical management, consensus regarding surgical approach was rather equivocal. We concluded that pelvic actinomycosis should be strongly suspected in women with presumed ovarian cancer of atypical presentation and a history of intrauterine devices (IUD). ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/2053-6844-1-5) contains supplementary material, which is available to authorized users. BioMed Central 2014-12-10 /pmc/articles/PMC4877746/ /pubmed/27231558 http://dx.doi.org/10.1186/2053-6844-1-5 Text en © Laios et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Laios, Alex
Terekh, Iryna
Majd, Hooman Soleymani
Pathiraja, Pubudu
Manek, Sanjiv
Haldar, Krishnayan
Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
title Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
title_full Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
title_fullStr Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
title_full_unstemmed Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
title_short Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
title_sort differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877746/
https://www.ncbi.nlm.nih.gov/pubmed/27231558
http://dx.doi.org/10.1186/2053-6844-1-5
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