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Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions

BACKGROUND: Protein kinase C δ (PKCδ) is known to be an important regulator of apoptosis, having mainly pro- but also anti-apoptotic effects depending on context. In a previous study, we found that PKCδ interacts with the pro-apoptotic protein Smac. Smac facilitates apoptosis by suppressing inhibito...

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Detalles Bibliográficos
Autores principales: Holmgren, Christian, Cornmark, Louise, Lønne, Gry Kalstad, Masoumi, Katarzyna Chmielarska, Larsson, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877760/
https://www.ncbi.nlm.nih.gov/pubmed/27216037
http://dx.doi.org/10.1186/s12858-016-0065-x

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