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Postoperative pulmonary complications following major elective abdominal surgery: a cohort study

BACKGROUND: Postoperative pulmonary complications (PPC) are an under-reported but major cause of perioperative morbidity and mortality. The aim of this prospective, contemporary, multicentre cohort study of unselected patients undergoing major elective abdominal surgery was to determine the incidenc...

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Autores principales: Patel, Kamlesh, Hadian, Fatemeh, Ali, Aysha, Broadley, Graham, Evans, Kate, Horder, Claire, Johnstone, Marianne, Langlands, Fiona, Matthews, Jake, Narayan, Prithish, Rallon, Priya, Roberts, Charlotte, Shah, Sonali, Vohra, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877761/
https://www.ncbi.nlm.nih.gov/pubmed/27222707
http://dx.doi.org/10.1186/s13741-016-0037-0
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author Patel, Kamlesh
Hadian, Fatemeh
Ali, Aysha
Broadley, Graham
Evans, Kate
Horder, Claire
Johnstone, Marianne
Langlands, Fiona
Matthews, Jake
Narayan, Prithish
Rallon, Priya
Roberts, Charlotte
Shah, Sonali
Vohra, Ravinder
author_facet Patel, Kamlesh
Hadian, Fatemeh
Ali, Aysha
Broadley, Graham
Evans, Kate
Horder, Claire
Johnstone, Marianne
Langlands, Fiona
Matthews, Jake
Narayan, Prithish
Rallon, Priya
Roberts, Charlotte
Shah, Sonali
Vohra, Ravinder
author_sort Patel, Kamlesh
collection PubMed
description BACKGROUND: Postoperative pulmonary complications (PPC) are an under-reported but major cause of perioperative morbidity and mortality. The aim of this prospective, contemporary, multicentre cohort study of unselected patients undergoing major elective abdominal surgery was to determine the incidence and effects of PPC. METHODS: Data on all major elective abdominal operations performed over a 2-week period in December 2014 were collected in six hospitals. The primary outcome measure of PPC at 7 days was used. Univariate and multivariate analyses were performed to investigate how different factors were associated with PPC and the effects of such complications. RESULTS: Two hundred sixty-eight major elective abdominal operations were performed, and the internal validation showed that the data set was 99 % accurate. Thirty-two (11.9 %) PPC were reported at 7 days. PPC was more common in patients with a history of chronic obstructive pulmonary disease compared to those with no history (26.7 vs. 10.2 %, p < 0.001). PPC was not associated with other patient factors (e.g. age, gender, body mass index or other comorbidities), type/method of operation or postoperative analgesia. The risk of PPC appeared to increase with every additional minute of operating time independent of other factors (odds ratio 1.01 (95 % confidence intervals 1.00–1.02), p = 0.007). PPC significantly increase the length of hospital stay (10 vs. 3 days). Attendance to the emergency department within 30 days (27.3 vs. 10.6 %), 30-day readmission (21.7 vs. 9.9 %) and 30-day mortality (12.5 vs. 0.0 %) was higher in those with PPC. CONCLUSIONS: PPC are common and have profound effects on outcomes. Strategies need to be considered to reduce PPC. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13741-016-0037-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-48777612016-05-25 Postoperative pulmonary complications following major elective abdominal surgery: a cohort study Patel, Kamlesh Hadian, Fatemeh Ali, Aysha Broadley, Graham Evans, Kate Horder, Claire Johnstone, Marianne Langlands, Fiona Matthews, Jake Narayan, Prithish Rallon, Priya Roberts, Charlotte Shah, Sonali Vohra, Ravinder Perioper Med (Lond) Research BACKGROUND: Postoperative pulmonary complications (PPC) are an under-reported but major cause of perioperative morbidity and mortality. The aim of this prospective, contemporary, multicentre cohort study of unselected patients undergoing major elective abdominal surgery was to determine the incidence and effects of PPC. METHODS: Data on all major elective abdominal operations performed over a 2-week period in December 2014 were collected in six hospitals. The primary outcome measure of PPC at 7 days was used. Univariate and multivariate analyses were performed to investigate how different factors were associated with PPC and the effects of such complications. RESULTS: Two hundred sixty-eight major elective abdominal operations were performed, and the internal validation showed that the data set was 99 % accurate. Thirty-two (11.9 %) PPC were reported at 7 days. PPC was more common in patients with a history of chronic obstructive pulmonary disease compared to those with no history (26.7 vs. 10.2 %, p < 0.001). PPC was not associated with other patient factors (e.g. age, gender, body mass index or other comorbidities), type/method of operation or postoperative analgesia. The risk of PPC appeared to increase with every additional minute of operating time independent of other factors (odds ratio 1.01 (95 % confidence intervals 1.00–1.02), p = 0.007). PPC significantly increase the length of hospital stay (10 vs. 3 days). Attendance to the emergency department within 30 days (27.3 vs. 10.6 %), 30-day readmission (21.7 vs. 9.9 %) and 30-day mortality (12.5 vs. 0.0 %) was higher in those with PPC. CONCLUSIONS: PPC are common and have profound effects on outcomes. Strategies need to be considered to reduce PPC. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13741-016-0037-0) contains supplementary material, which is available to authorized users. BioMed Central 2016-05-23 /pmc/articles/PMC4877761/ /pubmed/27222707 http://dx.doi.org/10.1186/s13741-016-0037-0 Text en © Patel et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Patel, Kamlesh
Hadian, Fatemeh
Ali, Aysha
Broadley, Graham
Evans, Kate
Horder, Claire
Johnstone, Marianne
Langlands, Fiona
Matthews, Jake
Narayan, Prithish
Rallon, Priya
Roberts, Charlotte
Shah, Sonali
Vohra, Ravinder
Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
title Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
title_full Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
title_fullStr Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
title_full_unstemmed Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
title_short Postoperative pulmonary complications following major elective abdominal surgery: a cohort study
title_sort postoperative pulmonary complications following major elective abdominal surgery: a cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877761/
https://www.ncbi.nlm.nih.gov/pubmed/27222707
http://dx.doi.org/10.1186/s13741-016-0037-0
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