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Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience

BACKGROUND: Percutaneous pulmonary valvuloplasty is well established treatment of choice in pulmonary valve stenosis. AIM: The aim of our study was to present our experience with the interventional technique, its immediate and mid-term effectiveness as well as its complication rate. MATERIAL AND MET...

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Autores principales: Idrizi, Shpend, Milev, Ivan, Zafirovska, Planinka, Tosheski, Goce, Zimbakov, Zan, Ampova-Sokolov, Vilma, Angjuseva, Tanja, Mitrev, Zan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Immunobiology and Human Genetics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877828/
https://www.ncbi.nlm.nih.gov/pubmed/27275259
http://dx.doi.org/10.3889/oamjms.2015.089
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author Idrizi, Shpend
Milev, Ivan
Zafirovska, Planinka
Tosheski, Goce
Zimbakov, Zan
Ampova-Sokolov, Vilma
Angjuseva, Tanja
Mitrev, Zan
author_facet Idrizi, Shpend
Milev, Ivan
Zafirovska, Planinka
Tosheski, Goce
Zimbakov, Zan
Ampova-Sokolov, Vilma
Angjuseva, Tanja
Mitrev, Zan
author_sort Idrizi, Shpend
collection PubMed
description BACKGROUND: Percutaneous pulmonary valvuloplasty is well established treatment of choice in pulmonary valve stenosis. AIM: The aim of our study was to present our experience with the interventional technique, its immediate and mid-term effectiveness as well as its complication rate. MATERIAL AND METHODS: The study included 43 patients, where 33 (74%) of them were children between the age of 1 month and 15 years. RESULTS: The procedure was successful in 38 patients or 90%. Mean peak to peak transvalvular gradient was reduced from 91.2 mmHg (55-150 mmHg) to 39.1 mmHg (20-80 mmHg). Follow- up of patients was between 2 and 13 years and included echocardiographic evaluation of pulmonary valve gradient, right heart dimensions and function as well as assessment of pulmonary regurgitation. We experienced one major complication pericardial effusion in a 5 months old child that required pericardiocenthesis. Six patients (13.9%) required a second intervention. During the follow up period there was significant improvement of right heart function and echocardiography parameters. Mild pulmonary regurgitation was noted in 24 (55%) patients, and four (9%) patients developed moderate regurgitation, without affecting the function of the right ventricle. CONCLUSIONS: Percutaneous pulmonary valvuloplasty is an effective procedure in treatment of pulmonary stenosis with good short and mid-term results.
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spelling pubmed-48778282016-06-06 Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience Idrizi, Shpend Milev, Ivan Zafirovska, Planinka Tosheski, Goce Zimbakov, Zan Ampova-Sokolov, Vilma Angjuseva, Tanja Mitrev, Zan Open Access Maced J Med Sci Clinical Science BACKGROUND: Percutaneous pulmonary valvuloplasty is well established treatment of choice in pulmonary valve stenosis. AIM: The aim of our study was to present our experience with the interventional technique, its immediate and mid-term effectiveness as well as its complication rate. MATERIAL AND METHODS: The study included 43 patients, where 33 (74%) of them were children between the age of 1 month and 15 years. RESULTS: The procedure was successful in 38 patients or 90%. Mean peak to peak transvalvular gradient was reduced from 91.2 mmHg (55-150 mmHg) to 39.1 mmHg (20-80 mmHg). Follow- up of patients was between 2 and 13 years and included echocardiographic evaluation of pulmonary valve gradient, right heart dimensions and function as well as assessment of pulmonary regurgitation. We experienced one major complication pericardial effusion in a 5 months old child that required pericardiocenthesis. Six patients (13.9%) required a second intervention. During the follow up period there was significant improvement of right heart function and echocardiography parameters. Mild pulmonary regurgitation was noted in 24 (55%) patients, and four (9%) patients developed moderate regurgitation, without affecting the function of the right ventricle. CONCLUSIONS: Percutaneous pulmonary valvuloplasty is an effective procedure in treatment of pulmonary stenosis with good short and mid-term results. Institute of Immunobiology and Human Genetics 2015-09-15 2015-08-25 /pmc/articles/PMC4877828/ /pubmed/27275259 http://dx.doi.org/10.3889/oamjms.2015.089 Text en Copyright: © 2015 Shpend Idrizi, Ivan Milev, Planinka Zafirovska, Goce Tosheski, Zan Zimbakov, Vilma Ampova-Sokolov, Tanja Angjuseva, Zan Mitrev. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Science
Idrizi, Shpend
Milev, Ivan
Zafirovska, Planinka
Tosheski, Goce
Zimbakov, Zan
Ampova-Sokolov, Vilma
Angjuseva, Tanja
Mitrev, Zan
Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience
title Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience
title_full Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience
title_fullStr Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience
title_full_unstemmed Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience
title_short Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience
title_sort interventional treatment of pulmonary valve stenosis: a single center experience
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877828/
https://www.ncbi.nlm.nih.gov/pubmed/27275259
http://dx.doi.org/10.3889/oamjms.2015.089
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