Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways

BACKGROUND: The hexapeptide SLIGRL-amide activates protease-activated receptor-2 (PAR-2) and mas-related G protein-coupled receptor C11 (MRGPRC11), both of which are known to be expressed on populations of sensory nerves. SLIGRL-amide has recently been reported to inhibit influenza A (IAV) infection...

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Detalles Bibliográficos
Autores principales: Chang, Amy Y., Mann, Tracy S., McFawn, Peter K., Han, Liang, Dong, Xinzhong, Henry, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877944/
https://www.ncbi.nlm.nih.gov/pubmed/27215903
http://dx.doi.org/10.1186/s12931-016-0378-8

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